Psychedelic Retreat
Luxury All-Inclusive Psilocybin and DMT Retreat Program
Peak experiences that translate into long-term results.
For those who want to go beyond a clinical setting, our outdoor sessions offer a different kind of container. One shaped by nature itself.
A neuroscience focused, medically supported psychedelic retreat in Mexico.
Here, psilocybin and DMT are used as complementary tools, each bringing its own perspective to a carefully guided process. Together, they expand the map of possibilities.
Eleusinia operates within Mexico’s legal framework, on a private 100-acre natural setting, with experienced facilitators and support before, during, and after the retreat.
Sessions Completed
Private Retreat Center
For the Discerning Traveler
Most retreats are designed as complete experiences. You arrive, you go through something significant, you leave.
Eleusinia was built differently. Every guest joins the Eleusinia Network, a private alumni community of 300 to 400 active members. Weekly integration meetings, facilitated by the clinical team, have been running for five years. The Eleusinia Podcast has more than 75 guest interviews recorded weeks, months, and years after the retreat.
The peak is real. So is everything that comes after it.
Think you know psychedelics? Not like this.
At Eleusinia, empowerment means putting the tools directly in your hands. You’ll gain a deep understanding of how psilocybin and DMT work in the brain, why they matter, and how to navigate these experiences safely. You’ll also learn practical skills like mushroom cultivation and DMT extraction.
We strip away the mystique and the gatekeeping that keep most people dependent on others.
After the retreat, the journey continues with weekly integration meetings and a vibrant online community.
This is about real mastery, and it lasts.
Until you’ve worked with both psilocybin and DMT, you’ve only glimpsed what’s possible.
At Eleusinia, each has its place, chosen for what it uniquely brings to the journey.
These experiences unfold not in crowded rooms, but in open-air gardens and private outdoor settings.
This isn’t one size fits all. It’s designed to meet you where you are, with the support and freedom to explore in a way that’s truly your own.
Together, these tools deepen the path in ways one alone cannot.
If “medical support” at past retreats meant little more than a safety net in case something went wrong, you’ve never really experienced true care.
At Eleusinia, our medical team isn’t tucked away in the background. They’re present, integrated, and proactive. They’re focused not just on safety, but on your comfort and depth of journey.
With a prescribing doctor and full support team on-site, you have the power of modern medicine alongside ancient tools.
That’s not just reassurance. That’s transformation made possible.
People often hear about the outcomes of a retreat, but not the experience itself.
This is a closer look at what unfolds each day during an 8-day psilocybin retreat, including the quieter moments in between.
What Exactly Is A Neuroscience-Focused Psychedelic Retreat?
We masterfully integrate modern research with a profound understanding of the effects of psychedelics on the brain. Here, you’ll encounter a unique blend of scientific rigor and consciousness exploration to unlock your full potential.
Psilocybin and DMT increase connectivity, communication, and synchrony between different brain regions. These remarkable substances serve as potent tools for elevating consciousness, deepening spirituality, and potentially shielding the brain and arteries from age-related illnesses like dementia and atherosclerosis. Additionally, they offer effective support for individuals managing chronic pain or mental health challenges by harnessing anti-inflammatory properties and promoting neuroplasticity.
In our retreats, we skillfully harmonize the worlds of science and tradition, ensuring you benefit from the best of both realms.
Who visits Eleusinia?
Is Eleusinia right for you?
Why choose a psychedelic retreat in mexico?
With retreats popping up across the US, Europe, and the Caribbean, options aren't the issue - value is. Mexico just offers more. Rooted in tradition and supported by a thriving medical tourism infrastructure, it’s where our US-trained, licensed professionals have the greatest freedom to use every available tool - including medications and approaches not accessible elsewhere. The result? Better care, more effective support, and a stronger return on your investment.
welcoming guests also navigating
Not just a retreat: we're a working mushroom farm
Most retreats can’t tell you where their mushrooms come from. We can tell you exactly - because we grew them, from sterilized grain to the moment they're harvested.
Experience the only retreat that is also a fully functional mushroom farm and mycology center.
Mental Reset
At Eleusinia, about 30% of guests arrive seeking a mental reset, whether it's for overcoming a professional rut, handling major life changes, improving relationships, or exploring their inner consciousness.
Psychological Wellness
Approximately 40% of Eleusinia visitors seek to improve mental health, inspired by promising psychedelic clinical trials for depression, OCD, and addiction.
Pain Management
Approximately 30% of Eleusinia visitors utilize our expertise in chronic pain management, harnessing the untapped potential of psychedelics for physical relief.
Retreat Reviews
matthew leonardApril 29, 2026 I've been to a number of psychedelic retreats. In my experience, a lot of them have various limitations, especially in terms of disorganization, insufficient or unqualified staffing, an inflexible approach, and lack of knowledgeable background for the medicine they're working with. The owners at Eleusinia are more knowledgeable and put more time, love, and thought into the program than any other that I've been to. Their neuroscientific approach and professional staff prevents any spiritual, linguistic, or cultural barriers that I've encountered at other retreats. Eleusinia especially stands out for their use of rescue medication when necessary to ensure a positive experience that gives you the maximum benefit, which almost all other retreats do not offer. Eleusinia rises above the other psychedelic retreats that I've experienced in that I have no constructive criticism to offer, and that's why I've been back four times in just a few years. Edan Bar-LevApril 22, 2026 I had a genuinely great experience at Eleusinia. This was my second retreat of this kind, as I’ve been trying to go deeper and better understand myself and life in general. What really sets Eleusinia apart is how small and intentional it is. There are no more than 14 people, which makes the whole experience feel personal and focused. The owners are there every day, fully involved, and you can tell they truly care about each person having a meaningful experience. The accommodations were excellent. My room and bathroom felt very high-end, and the overall property was beautiful and well maintained. The staff across the board were top-notch, and the food was consistently great. I’d recommend this place to someone just starting to explore their subconscious, as well as someone more experienced who’s looking to try a different approach with psilocybin or DMT, especially if they’ve already worked with things like ayahuasca or mescaline. One thing to know going in: this is less about spirituality and more about using these tools in a therapeutic, practical way, including reducing reliance on traditional pharmaceuticals. If you’re looking for a heavily spiritual experience, this may not be that. But the medical team is excellent, and I felt very well taken care of throughout. Overall, I left feeling clearer, more grounded, and genuinely grateful for the experience. It’s the kind of place that stays with you after you leave, in a good way. If you’re thoughtful about your growth and open to a different kind of approach, Eleusinia is absolutely worth it. Kristina VecsesiApril 21, 2026 Eleusinia saved my life, not in a casual context. I was knocking on death’s door before I arrived. The level of care and compassion extended by their professional team of wise and experienced staff surpassed my expectations from every angle. Almost 5 months and 2 visits later I am greeting the day with gratitude and joy. I cannot endorse this place highly enough and look forward to visiting again soon and forevermore. Thank you Curandera and Jess and Emilio, and Ari and Andrew and Ana and Jay and Julio and Claudia and the rest of the team. Alliance NXApril 16, 2026 "Taking the risk to attend this retreat was one of the best decisions I’ve made. They created a safe and supportive container for deep work. The meditation sessions were powerful and the food was amazing. If you are on the fence, I highly recommend this experience. It was truly a gift." Thank you to the entire Eleusinia team!🙏 ShawnaMarch 23, 2026 It has taken me some time to communicate what I experienced at Eleusinia. I went there with no expectations. I just needed some relief from the grief and trauma that I couldn’t heal from. I was paralyzed emotionally and had lost my passion for living, an internal fault line, a void. Nothing in Western medicine that I had tried was working. What I encountered at Eleusinia was an extraordinary cathartic journey back to my true self and peace, finally peace. Really, a miracle for me to find such an authentic, science-based solution delivered by such caring experts in an incredibly beautiful setting. I have already booked my return to Eleusinia to further explore my inner potential and be free to be happy. I didn’t think it was possible. Thank you, Eleusinia damien brooksMarch 21, 2026 A truly life altering experience. The support staff had a perfect mix of scientific and spiritual backgrounds, allowing for integration of the experience for people of all walks of life, while allowing for further exploration of the psychedelic experience from a lens that you may not otherwise identify with. The resort itself could not have been more idealic for psychedelic healing, the natural beauty offering a safe setting and amazing visuals. The structure of the experience is prepared in a way to minimize discomfort, giving participants the chance to dive into their journey without nausea or distraction from other participants. Eleusinia offers 3 different types of sessions, and offers you the option to scale back or increase between experiences, allowing you to maintain a degree of control, or to truly pursue your deepest inner mind. There are also additional activities available for the spiritual and science minded, to help you expand your journey. The worst part of the experience is the flight home. BENMarch 20, 2026 I spent 3 years deciding how and where to explore psilocybin. After attending the 8 day retreat one of my sources of gratitude was choosing Eleusinia. I can’t imagine anything that would have made the experience more enriching, valuable or comfortable. Jessica, who designed the program overlooked no detail. Her vision and understanding of her attendees can’t be exceeded. Jay, Emilio, Allison, Ari, Andrew, and all the behind the scenes support staff are not only fulfilling their duties, they’re doing it with zest and imagination. Having my first experiences with psilocybin and DMT at this retreat has affected my life in more positive ways than I can express. I leave this review to encourage anyone considering a journey like this to take this step forward in life. And I wholeheartedly suggest choosing Eleusinia. christy martinMarch 20, 2026 BEYOND BRILLIANT 🍃🍃🍃🍃🍃🍃 Jessica and Jay have co-created ELEUSINIA, a stunning retreat space on a 100 acre gated private compound that includes multiple verdant gardens, ancient trees, creeks, waterfalls, forests - and with all of that lush background - many birds, butterflies + other creatures to share this really beautiful special enclave. They offer an incredible series of curated experiences daily to guide you thru your plant medicine journey with the best of support systems available to include: * the aforementioned grounds to enable connectedness/oneness with nature * very comfortable private rooms with en suite baths * medical doctor + nurse practitioner for any potential needed medical care * curandera/shaman to grace you with their ancient spiritual knowledge + ceremonies * a meditation + a breath-work instructor to relax you into a blissful pre-experience state * a bodyworker + a massage therapist for your physical wellbeing * well trained chefs creating absolutely delicious + nutrition dense vegan or vegetarian meals, made with extreme love + care but most importantly, Jessica imparts her vast knowledge of hallucinogens - in particular Psilocybin + DMT (Mimosa tenuiflora) - the only two plant medicines used at this retreat. In addition, Jessica teaches classes + “where to” purchase links so you can learn to create your own DMT here-forward, to continue on your experiences independently. Lastly they offer an online community for former retreat goers to share information, thoughts + stories AND weekly integration meetups to help you continue you on your path with others of like mind. Personally speaking, this retreat was not always very easy for me, it was very cathartc + at one point, i didn’t really want to continue. Headache, flu like feelings/achiness, some sleeplessness however when all of those symptoms dissipated, i felt an incredible lightness of being. And then the sleep was deep, the mind peaceful yet alert. I am still processing everything (we just left yesterday) but i honestly feel that there isn’t anyone or anything that even comes close to the high standards + level of what Jessica + Jay and their incredibly compassionate + competent Eleusinia staff offer. It’s life changing, so much for the better. Definitely the most powerful, profound i have experienced in my life thus far. paulcmillerfilmsMarch 12, 2026 2025 was the year I decided to make whole-sale changes to my life. At age 60, when my career pretty much died overnight, I discovered a whole new life and experiences. Taking a leap, I decided to move to Europe. At the same time, coming off of a breakup, I decided to handle my inter-life too. My connection style is of the anxious variety and I wanted to shift it to something more stable. I wanted to break the hex of codependency, which I finally realized I consistently invited into my life. My friend shared how much she got out of her Eleusinia retreat so I decided to take the plunge and signed up to attend the early March retreat of 2026. I didn’t know what to expect and I went into the process focussing on myself. At first, it was hard to grant myself permission to be catered to and taken care of (something that the staff of Eleusinia was great at), but once I surrendered to the process, I was excited to move forward. While I was interested in the Macrodose, I had heard so much about the DMT experience, I was curious about that too. After all was said and done, I found both experiences rewarding. Since it has only been a few days since my experience, I am still processing, but I definitely feel that I am thinking differently and better able challenge old beliefs. Besides just the visual experience that was far beyond what I could have ever imagined from a psychedelic experience, I feel there’s been a shift in me. I can’t say there was any specific moment that was a breakthrough but I will say that the activities before, during, and after the psychedelic experiences were very impactful. I was able to experience first hand, just how much I live in fear and apprehension on a daily basis. I feel with my acknowledgement, I can and am making choices differently than I have in the past. I intend to keep up the practice. Overall, it was a great experience beyond expectations. The staff was knowledgeable and truly cared about all of the participant’s experiences. The venue was gorgeous and provided an expansive visual feast, even more so once in the actual psychedelic experience kicked in. The retreat was informative and the support available after is phenomenal. This is the beginning of my journey and I am grateful to be introduced to this world in such an informative, caring fashion! Jack WadeMarch 9, 2026 I felt welcomed from the moment I arrived to waving goodbye on the final day. During the retreat I felt supported and cared for by every member of the staff. I left feeling educated, well informed, fresh and connected to a deeper part of myself (which in turn allows me to connect to others deeper). If I could give 10 stars I would 🙏Google rating score: 4.9 of 5, based on 114 reviews
Our Articles
The Eleusinia Story
Jessica established Eleusinia, a psilocybin retreat in Mexico, after finding lasting relief from Hemicrania Continua - a debilitating headache condition - through psilocybin treatment. Located in Mexico, Eleusinia embodies her vision of an authentic cultural psychedelic retreat experience, blending the latest neuroscience with high standards for personalized care, comfortable accommodations, and balanced wellness support.
We value your privacy
At Eleusinia Retreat, we are committed to protecting your privacy. To reflect the discretion we offer and the caliber of our guests, we maintain a firm no-photography policy and never share identifiable photos on social media.